Notes on gut health, honestly.

Evidence-based writing on microbiome science and the claims industry we're trying to fix.

Apr 22, 2026

The biggest diet-microbiome study didn't fit our framework. So we built a controlled bridge.

The Human Phenotype Project reports diet scores, not food-level coefficients. We recovered food-level signal and selectively integrated it into our multi-cohort framework.

Apr 21, 2026

To extend beyond older microbiome cohorts, we had to build a bridge

We bridged newer shotgun/CLR cohorts back to our validated 16S reference layer using empirical anchor calibration across a five-cohort panel.

Apr 20, 2026

Before building on public microbiome studies, we checked whether they agree

We compared published coefficient tables from three large 16S diet-microbiome cohorts. Among significant shared signals, 89% pointed the same way.

Apr 20, 2026

Welcome to the Biome Bliss blog

A first look at why we started Biome Bliss — and why 88% of gut-health claims don't survive scientific review.